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There is a smoking household link, and it is shocking to owners who were unaware of the risks, he says

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[156] found that CSE enhanced both mRNA and protein expression of IL-8, which was important for neutrophil chemotaxis, accompanying with phosphorylation of p38 MAPK and MEK2 in human pulmonary cells

This increases the risk of heart disease, much like clogging up the pipes in your home plumbing system.